U.S. stocks opened with broad gains across the semiconductor, storage, and optical communication sectors. AXTI surged more than 15%, while SanDisk, AAOI, and LITE each rose over 10%.

The combined open interest (OI) value of two Anthropic pre-market perpetual contracts on Hyperliquid has exceeded $311 million. Among them, the ANT contract from Trade.xyz has an OI of $109.37 million, up around 30% from $84.04 million on November 10. The ANTH contract from EntropyIO carries an OI of $201.81 million. Additionally, Anthropic’s pre-market perpetual contracts have surged over 10% in the past 8 hours, trading at a roughly 37% premium to the upper end of its IPO price range.

Data from the BIT stock platform shows that the U.S. Dollar Index (DXY) has broken through its previous high from last month, rising to 102.95, the highest level since April last year.

，Coreweave(CRWV.O)CEO：英伟达并不是由一个人说了算的公司，他们将继续成为我们的重要合作伙伴。我们的建设计划没有出现延误，也没有以任何方式发生改变。看不到有任何因素会影响我们在美国境内交付数据中心的能力。

According to EmberCN’s monitoring, crypto venture capital firm Strobe Fund completed its full liquidation of ENA an hour ago by transferring its final 50 million ENA (valued at roughly $7.54 million) to Coinbase. Over the past 24 hours, the firm has transferred a total of 101.95 million ENA to Coinbase, worth about $15.6 million. All 142.9 million ENA in its allocation have been sold, totaling approximately $32.95 million at an average price of $0.23.

Beating AI Express: Google DeepMind has announced the launch of its next-generation DNA sequence model, AlphaGenome 2, which predicts how DNA sequences and their variants affect specific human cell types to help study disease causes at the cellular level. Building on last year’s AlphaGenome, the model refines predictions from coarse tissue averages to individual cell types and states, with a redesigned architecture. Officials state that AlphaGenome 2 identifies nearly twice as many variants that alter cellular gene expression as the previous leading models. Trained on human and mouse population and single-cell data, its training set includes over 107 million single-cell atlases covering 68 tissues, turning static cell maps into predictive engines for human genetics. A conditional model, AlphaGenome 2 generates predictions for one tissue, cell type, or state at a time, adapts to new single-cell data from researchers without retraining, and imputes missing experimental data. The model is now open for non-commercial research via the AlphaGenome API; commercial research access is offered as a restricted non-public preview. Officials stress that AlphaGenome and AlphaGenome 2 are for research only, and have not been approved for clinical or diagnostic use.

Pyth Network announced it has become a distributor of NYSE BQT, the New York Stock Exchange’s real-time Level 1 market data product, with the relevant data now available through the Pyth Data Marketplace. The product covers real-time quotes and trades from all five stock trading platforms under the NYSE Group, serving U.S. stocks and ETFs. Three weeks ago, Pyth became an approved external dealer for Nasdaq Basic; after integration, applications can access real-time data from both trading platforms via the same channel. NYSE BQT also offers latest trade prices, major market closing prices, real-time aggregated trading volume, and market status updates including trading halts, resumptions, and short selling restrictions. Customers must apply for authorization directly from the NYSE before receiving the data through Pyth.